Fig. 4From: The role of pyroptosis in modulating the tumor immune microenvironmentRemodeling the TIME by targeting pyroptosis. Several treatments targeting pyroptosis have been proposed or developed to overcome the immunosuppression microenvironment, including evocation of GSDMD/GDDME-mediated pyroptosis, prevention of inflammasome activation, antagonizing IL-1β, increase of IL-18. ICB, immune checkpoint blockadeBack to article page