Fig. 5
From: Integrated multiomic approach for identification of novel immunotherapeutic targets in AML
Validation of putative targets in independent samples by flow cytometry. A Expression of potential targets on independent patient samples and healthy donor bone marrow specimens by FACS, showing significant expression on healthy mature monocytes and granulocytes for CD148 or HSPCs for ITGA4. *p < 0.05 B Distribution of Integrin beta-7 on healthy donors showing favorable (low) expression on healthy hematopoietic tissues