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Table 2 Clinical-pathological features of Cohort II pLGG patients

From: MiR-1248: a new prognostic biomarker able to identify supratentorial hemispheric pediatric low-grade gliomas patients associated with progression

Cohort II pLGG patients

Sample code

Age (years)

Gender

Site of onset

Histology

Type of resection

Progression

Progression Free Survival (months)

Overall Survival (months)

Mutational status

ICGC_PA104

3

F

Md Supra

PA

NTR

W/O

6

6

WT

ICGC_PA144

2

F

Md Supra

PA

NTR

W/O

4

4

CLCN6:BRAF Ex2:Ex11); BRAF p.E451D

ICGC_PA14

5

F

Md Supra

PA

NTR

W/O

23

23

K15B9

ICGC_PA159

5

M

Md Supra

PA

NTR

W/O

3

3

QKI:NTRK2 (Ex6:Ex16)

ICGC_PA4

1

M

Md Supra

PA

NTR

W/O

22

22

K16B9

ICGC_PA54

4

F

Md Supra

PA

NTR

WITH

4

12

WT

ICGC_PA69

6

F

Md Supra

PA

NTR

WITH

17

17

NF1 Large deletion (somatic); p.Q1174fs (somatic); FGFR1 p.N546K

ICGC_PA71

2

F

Md Supra

PA

NTR

WITH

5

16

NF1 p.Q959X (germline); large deletion (somatic)

ICGC_PA84

9

M

Md Supra

PA

NTR

W/O

10

10

FGFR1 p.K656E; PTPN11 p.E76A

  1. Md Midline, PA Pilocytic Astrocytoma, NTR Near Total Resection, WITH With progression, W/O Without progression