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Table 1 Characteristics of the study population

From: Bone morphogenetic protein 2 is a new molecular target linked to non-alcoholic fatty liver disease with potential value as non-invasive screening tool

 

NL (n = 75)

NAFL (n = 56)

NASH (n = 59)

Age (years)

46.58 ± 14.11

52.51 ± 14.15*

55.42 ± 11.1***

Gender (female/male, %)

13.33 / 86.67

33.9 / 66.1

44.07 / 55.93

BMI (kg/m2)

27.57 ± 5.1

28.46 ± 3.96

34.14 ± 6.56***###

Glucose (mg/dL)

92.6 ± 19.46

99.23 ± 13.92***

119.35 ± 48.5***

Insulin (μU/L)

7.67 ± 4.44

10.06 ± 5.36**

21.38 ± 15.11***###

HOMA-IR

1.83 ± 1.31

2.52 ± 1.53***

6.19 ± 4.92***###

Triglycerides (mg/dL)

122.33 ± 66.78

135.52 ± 56.47*

176.22 ± 120.84***##

Total cholesterol (mg/dL)

191.17 ± 38.48

203.96 ± 39.13

192.44 ± 45.29

AST (IU/L)

17.96 ± 5.69

21.59 ± 8.65*

42.12 ± 25.95***###

ALT (IU/L)

18.52 ± 10.1

27.12 ± 17.27***

54.73 ± 33.02***###

GGT (IU/L)

32.36 ± 29.51

48.82 ± 52.26**

117.24 ± 194.33***###

Steatosis (%)

 Grade 0

100%

 

8.5%

 Grade 1

 

73.21%

28.8%

 Grade 2

 

17.86%

33.9%

 Grade 3

 

8.93%

28.8%

Ballooning and lobular inflammation (%)

 Grade 0

100%

87.5%

1.85%

 Grade 1

 

12.5%

37.04%

 Grade 2

  

51.85%

 Grade 3

  

9.26%

Fibrosis (%)

 Grade 0

100%

100%

13.56%

 Grade 1

  

35.6%

 Grade 2

  

18.64%

 Grade 3

  

20.34%

 Grade 4

  

11.86%

  1. NL Normal liver, NAFL Nonalcoholic fatty liver, NASH Nonalcoholic steatohepatitis, BMI Body mass index, HOMA-IR Homeostatic model assessment-insulin resistance, AST Aspartate aminotransferase, ALT Alanine aminotransferase, GGT Gamma-glutamyltransferase
  2. Data are shown as mean ± SD or as number of cases (%)