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Table 4 Latest results of studies of emerging therapies

From: EGFR exon 20 insertion mutations in advanced non-small-cell lung cancer: current status and perspectives

Treatment (reference)

N

Line

ORR (%)

mPFS (months)

mOS (months)

Poziotinib [56]

115

≥2

14.8

4.2

NA

Mobocertinib [57]

114

≥2

28

7.2

24

Amivantamab [58]

81

≥2

40

8.3

22.8

CLN-081 [59]

42

≥2

31

NA

NA

DZD9008 [60]

56

≥2

37.5

NA

NA

Furmonertinib [61]

10

≥2

60

NA

NA