Nonsmall Cell Lung Cancer (NSCLC)
IFN-α-JAK-STAT1 axis activated, promoting invision and metastasis .
Glioblastoma multiform (GBM)
Promoting Migration and invision .
Ovarian serous cystadeno carcinoma
Bcl2 levels downregulated.
Promoting apoptotic .
Brain-trophic metastatic MDA-MB-435-LvBr2 (LvBr2) cells
Promoting Migration and invision of LvBr2 cells .
Esophageal squamous cell carcinoma (ESCC)
enhance the stability of ZEB1 and ZEB2 mRNAs.
promoting cell EMT and migration in ESCC .
Oral squamous cell carcinoma (OSCC)
regulate AK4 mRNA stability.
reduced the radiosensitivity of OSCC cells .
trigger IFN response
inhibit proliferation and tumor growth .
URT of gene
drive CR- and UTR-APA in MTHFD1L .
Most of cancers
As a reader
has a potential as a biomaker.