Fig. 8From: KSR2-14–3-3ζ complex serves as a biomarker and potential therapeutic target in sorafenib-resistant hepatocellular carcinomaSchematic illustrating the mechanism by which KSR2 in regulates liver cancer growth and progression. In this proposed model, KSR2 can interact with 14–3-3ζ and form a complex, activating the Ras–Raf–MEK–ERK signaling pathway and thereby leading to the proliferation and growth of HCC cellsBack to article page