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Fig. 1 | Biomarker Research

Fig. 1

From: KSR2-14–3-3ζ complex serves as a biomarker and potential therapeutic target in sorafenib-resistant hepatocellular carcinoma

Fig. 1

KSR2 is up-regulated in tumor tissues based on publicly available expression data. A The protein expression of KSR2 in various cancer tissues in the Human Protein Atlas database. B Bubble plot of survival curves for various malignant cancers. C Analysis of KSR2 expression and OS survival in liver cancer samples from The Cancer Genome Atlas (TCGA) database. D KSR2 transcription data in 50 pairs of cancer and adjacent tissues in the TCGA database. E Schematic diagram of MAPK signaling pathway derived from KEGG. F Expression level of proliferating cell nuclear antigen (PCNA) and KSR2 in HCC. G The expression level of human Ki67 (MKI67) and KSR2 in HCC. H The expression level of histone deacetylase 1 gene (HDAC1) and KSR2 in HCC. *p < 0.05; **p < 0.01; ***p < 0.001

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Biomarker Research

ISSN: 2050-7771

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