Fig. 4

The accumulation scores of the partner proteins involve in the different pathways identified by IPA and GSEA. (A) The proteins with a high score in the effusion-associated (effusion+) cohort and non-effusion-associated (effusion—) cohort are represented by purple and blue, respectively. (B) The pathways that are positively and negatively associated with effusion-associated DLBCL detected by IPA. We highlighted the six maximum and minimum z-score values. The orange bars (positive z-score) indicate the activation of pathways, and the blue bars (negative z-score) indicate the inhibition of pathways