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Fig. 2 | Biomarker Research

Fig. 2

From: Deciphering genes associated with diffuse large B-cell lymphoma with lymphomatous effusions: A mutational accumulation scoring approach

Fig. 2

Genes affected by mutations in at least five effusion-associated (effusion+) DLBCL samples. (A) The samples containing at least one insertion/deletion (Indel) mutation, SNV, or both indel/SNV are represented by pink, blue, and green squares, respectively. The bottom of the figure shows the number of non-effusion-associated (effusion—) samples that contain SNVs and Indels. (B) Genes that have pathogenic mutation(s) in at least five effusion-associated (effusion+) DLBCL samples. Genes containing benign mutation(s) are shown by green (s < 0). Genes that have no pathogenic mutation and at least one variant of uncertain significance (VUS) are shown by white (s = 0). Genes that consist of at least one pathogenic mutation are shown by orange (0 < s < 10), red (10 < = s <= 20), or gray (s > 20) depending on the number of pathogenic mutations. The more positive score is interpreted as more pathogenic

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