Fig. 3
From: Detection and clinical significance of circulating tumor cells in colorectal cancer
Molecular profiling and clinical application of CTCs. a The difference in the metabolic profile between CTCs and lymphocytes of CRC patients. The analysis of the metabolic profile of CTCs shows the potential for the early diagnosis and differential diagnosis of cancer; b Fish images of different CTC phenotypes; c, d The hot map of genomic alterations in CTC and ctDNA in head and neck cancer patients and CRC patients. The associations between genomic alterations detected in ctDNA and CTC in CRC; e Multivariable analysis of overall survival of mCRC patients treated with regorafenib, by CTC counts at baseline. a Copyright Wiley 2019. Reproduced with permission from reference [93]; b Copyright Springer Nature 2018. Reproduced with permission from reference [100]; c, d Copyright Wiley 2019. Reproduced with permission from reference [115]; e Copyright Wiley 2020. Reproduced with permission from reference [118]