From: Blood biomarkers for mild traumatic brain injury: a selective review of unresolved issues
Marker | Study | Year | N | Time (hrs) | AUROC | Outcome |
---|---|---|---|---|---|---|
 |  |  |  |  |  | Predicted |
GFAP | Huebschmann [109] | 2020 | 121 | 0-12 | 0.69 | GOS-E >6 |
 | Pattinson [124] | 2020 | 59 | 0-12 | 0.40 | RTS <8 days |
NF-L | Shahim [72] | 2018 | 87 | 0-1 | 0.83 | RTS <15 days |
 | Shahim [84] | 2017 | 35 | 0-1 | 0.82 | RTS <6 days |
S100B | Shahim [85] | 2014 | 28 | 0-1 | 0.68 | Duration of PCS <6 days |
 | Babcock [125] | 2008 | 76 | 0-6 | 0.47 | Onset of PCS |
tau-A | Shahim [67] | 2016 | 28 | 0-1 | 0.87 | RTS <10 days |
tau-C | Shahim [67] | 2016 | 28 | 0-1 | 0.58 | RTS <10 days |
tau-T | Shahim [85] | 2014 | 28 | 0-1 | 0.91 | Duration of PCS <6 days |
 | Gill [87] | 2017 | 43 | 0-6 | 0.81 | RTS <10 days |
 | Pattinson [124] | 2020 | 59 | Recovered | 0.75 | RTS <8 days |
 | Shahim [72] | 2018 | 87 | 0-1 | 0.67 | RTS <15 days |
 | Pattinson [124] | 2020 | 55 | 24-48 | 0.66 | RTS <8 days |
 | Hossain [126] | 2020 | 105 | 0-24 | 0.56 | GOS-E >7 |