Table 6 Univariable and multivariable survival analysis for OS using Cox proportional hazards models
Group | Immune Biomarker | Univariable | Multivariable | ||
|---|---|---|---|---|---|
HR (95% CI) | p-value | HR (95% CI) | p-value | ||
Cohort A | ALCs > = 800 < 800 | 10.15 (2.46, 41.76) | 0.001 | 7.59 (1.33, 43.16) | 0.022 |
CD4 plus CD8 counts > = 500 < 500 | 2.90 (0.95, 8.84) | 0.061 | – | – | |
PD-L1 IHC > = 50% < 50% | 2.54 (0.56, 11.45) | 0.226 | – | – | |
TMB > = 10 < 10 | 0.42 (0.05, 3.51) | 0.423 | – | – | |
Cohort B | ALCs > = 800 < 800 | 2.38 (0.89, 6.35) | 0.084 | – | – |
CD4 plus CD8 counts > = 500 < 500 | 3.03 (1.12, 8.20) | 0.029 | 5.96 (1.60, 22.20) | 0.008 | |
PD-L1 IHC > = 50% < 50% | 3.18 (0.97, 10.45) | 0.056 | – | – | |
TMB > = 10 < 10 | 2.18 (0.71, 6.75) | 0.175 | – | – | |