Baseline Biomarker | Cohort A | Cohort B | Cohort C | P-value$ | |||
---|---|---|---|---|---|---|---|
N | Mean (±SD) | N | Mean (±SD) | N | Mean (±SD) | ||
WBC (×103 cells/μL) | 27 | 8.4 (±3.7) | 35 | 7.5 (±2.5) | 22 | 9.2 (±5.3) | 0.750 |
Hemoglobulin (gram/dL) | 27 | 12.5 (±2.0) | 35 | 12.7 (±1.9) | 22 | 12.8 (±1.4) | 0.805 |
Platelet count (× 103 cells/μL) | 27 | 305.2 (±126.6) | 35 | 298.8 (±125.9) | 21a | 281.0 (±89.8) | 0.884 |
ANC (×103 cells/μL) | 27 | 6.1 (±3.4) | 35 | 5.6 (±2.1) | 22 | 6.9 (±5.1) | 0.948 |
ALCs (×103 cells/μL) | 27 | 1.3 (±0.8) | 35 | 1.1 (±0.6) | 22 | 1.2 (±0.8) | 0.571 |
CD3 + CD4 + % | 27 | 40.6 (±11.1) | 35 | 45.3 (±12.7) | 22 | 44.5 (±9.5) | 0.222 |
CD3 + CD8 + % | 27 | 23.9 (±9.6) | 35 | 27.1 (±12.5) | 22 | 26.4 (±9.5) | 0.427 |
CD3 + % | 27 | 65.7 (±10.3) | 35 | 72.4 (±10.3) | 22 | 72.3 (±8.8) | 0.014 |
CD3 + CD4+ count (cells/μL) | 27 | 512.9 (±282.9) | 35 | 492.3 (±288.1) | 22 | 598.7 (±402.9) | 0.793 |
CD3 + CD8+ count (cells/μL) | 27 | 318.3 (±242.3) | 35 | 305.5 (±260.1) | 22 | 326.7 (±189.0) | 0.705 |
CD4/CD8 ratio | 27 | 2.0 (±0.9) | 35 | 2.1 (±1.3) | 22 | 1.9 (±0.9) | 0.934 |
CD4 plus CD8 count (cells/μL) | 27 | 831.2 (±451.7) | 35 | 797.8 (±431.7) | 22 | 925.4 (±555.5) | 0.831 |
dNLR | 27 | 3.4 (±3.0) | 35 | 3.2 (±1.5) | 22 | 3.4 (±2.5) | 0.668 |