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Table 2 Association between circulating endothelial EVs and clinical variables by repeated measures correlation

From: Circulating extracellular vesicles during pregnancy in women with type 1 diabetes: a secondary analysis of the CONCEPTT trial

EV population Clinical Variable r 95% CI p
Endothelial HbA1c 0.040 -0.072, 0.164 0.44
Mean CGM Glucose 0.091 -0.006, 0.186 0.06
% TIR (63-140mg/dl) -0.005 -0.129, 0.118 0.94
% TAR( >140mg/dl) 0.064 -0.060, 0.187 0.31
% TBR (<63mg/dl) -0.116 -0.236, 0.008 0.07
Glucose CV -0.012 -0.135, 0.112 0.85
Glucose SD 0.054 -0.070, 0.177 0.39
MAGE 0.129 0.005, 0.248 0.04
SBP 0.082 -0.035, 0.196 0.17
DBP 0.075 -0.043, 0.189 0.21
Platelet HbA1c 0.009 -0.107, 0.126 0.88
Mean CGM Glucose -0.111 -0.231, 0.013 0.08
% TIR (63-140mg/dl) 0.159 0.035, 0.276 0.01
% TAR( >140mg/dl) -0.138 -0.257, -0.014 0.03
% TBR (<63mg/dl) -0.055 -0.178, 0.068 0.38
Glucose CV -0.109 -0.229, 0.015 0.08
Glucose SD -0.147 -0.267, -0.025 0.02
MAGE -0.152 -0.271, -0.029 0.01
SBP 0.051 -0.066, 0.167 0.39
DBP 0.099 -0.017, 0.210 0.09
Leukocyte HbA1c 0.001 -0.116, 0.116 0.99
Mean CGM Glucose 0.003 -0.120, 0.127 0.95
% TIR (63-140mg/dl) 0.007 -0.116, 0.131 0.91
% TAR( >140mg/dl) 0.003 -0.121, 0.127 0.96
% TBR (<63mg/dl) -0.030 -0.154, 0.093 0.62
Glucose CV 0.008 -0.115, 0.132 0.89
Glucose SD 0.013 -0.110, 0.137 0.83
MAGE 0.001 -0.124, 0.123 0.99
SBP 0.179 0.064, 0.289 0.002
DBP 0.200 0.093, 0.315 0.001
  1. Significant relationships are bolded
  2. CGM continuous glucose monitoring, TIR time in range, TAR time above range, TBR time below range, CV coefficient of variation, SD standard deviation, MAGE mean amplitude of glycemic excursion, SBP systolic blood pressure, DBP diastolic blood pressure