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Fig. 2 | Biomarker Research

Fig. 2

From: Circulating extracellular vesicles during pregnancy in women with type 1 diabetes: a secondary analysis of the CONCEPTT trial

Fig. 2

High baseline endothelial EV levels are associated with adverse pregnancy outcomes. A: Forest plot depicting the relationship between baseline endothelial EV levels and pregnancy outcomes. B: Forest plot depicting the relationship between baseline endothelial EV levels and pregnancy outcomes after adjusting for the HbA1c and systolic and diastolic blood pressure. Maternal complications indicates the presence of oliguria, cerebral of visual symptoms, impairment of liver function, pulmonary edema or cyanosis, epigastric or right upper quadrant pain, or thrombocytopenia. Composite Neonatal Outcome: aggregate measure of pregnancy loss, birth injury, neonatal hypoglycaemia, and respiratory distress; LGA: Large for gestational age (> 90 percentile); Ventililation: respiratory distress requiring positive pressure ventilation

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