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Table 2 Summary of the discussed CAR-T for solid tumors

From: Novel strategies for immuno-oncology breakthroughs with cell therapy

Presenter Target Co-stimulatory molecule Tumor type Registration Number
Prasad Adusumilli Mesothelin CD28 Mesothelioma
TNBC
NCT02414269
Mesothelin CD28 with PD-1 dominant negative receptor Mesothelioma NCT04577326
Marcela Maus EGFRvIII 4-1BB Glioblastoma NCT02209376
Stanley Riddell ROR1 4-1BB ROR1 positive:
Lung cancer
TNBC
Hematologic malignancies
NCT02706392