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Fig. 2 | Biomarker Research

Fig. 2

From: Advances in chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma

Fig. 2

Four CAR-T cell products have been approved by the United States Food and Drug Administration (FDA): Yescarta for large B-cell lymphoma (LBCL) such as diffuse large B-cell lymphoma (DLBCL), transformed follicular lymphoma and primary mediastinal B-cell Lymphoma in 2017. Kymriah for LBCL in 2018. Then brexucabtagene autoleucel (KTE-X19) was approved by FDA for refractory / relapsed mantle cell lymphoma (R/R MCL) in 2020. In 2021, Breyanzi (liso-cel) was approval by FDA for patients with refractory / relapsed DLBCL (R/R DLBCL)

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