Fig. 1
From: The contribution of single-cell analysis of acute leukemia in the therapeutic strategy
A: leukemic cells each bearing a single drug resistance mechanism are depleted by polychemotheray, while B: leukemic cells with co-occurrence of various drug resistance mechanisms (Pgp+/MRP+/CLIP+/Gal9+/TGFb+/Bcl2+/GST+ = PAN-Resistant) hardly are eradicated by polychemotherapy, this co-occurrence in this AML sample is observed in C: 1% of leukemia blasts and D: 1% of leukemia stem cells defined as CD34 + CD38-CD123+