Fig. 3From: The REASON score: an epigenetic and clinicopathologic score to predict risk of poor survival in patients with early stage oral squamous cell carcinomaFunctional network analysis mapping. Functional enrichment analysis identifies the aggregation of differentially methylated genes onto pathways that aggregate to three concepts. a Dot plot of differentially enriched genes that map to the top ten most differentially perturbed methylated pathways (padjusted < 0.05). b The top 3 most statistically differentially methylated pathways are identified by a circle in grey and the fold change in differential methylation of component genes is rendered in color ranging from negative (green) to positive (red) fold change for each gene. The size of each circle is based on the number of genesBack to article page