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Fig. 2 | Biomarker Research

Fig. 2

From: The REASON score: an epigenetic and clinicopathologic score to predict risk of poor survival in patients with early stage oral squamous cell carcinoma

Fig. 2

Heat map and hierarchical clustering of differentially methylated genes demonstrate a distinct methylation signature in high-risk vs. low-risk OSCC patients. The figure represents a heat map of the 12 top differentially methylated genes between patients who survived to 5 years vs. those that died in the TCGA cohort. ABCA2 = ATP-binding cassette sub-family A member 2; CACNA1H = calcium voltage-gated channel subunit alpha1 H; CCNJL = cyclin J-like protein; GPR133 = adhesion G protein-coupled receptor D1; HGFAC = hepatocyte growth factor activator; HORMAD2 = HORMA domain containing 2; MCPH1 = microcephalin 1; MYLK = myosin light chain kinase; RNF216 = ring finger protein 216; SOX8 = SRY-box transcription factor 8; TRPA1 = transient receptor potential cation channel subfamily A member 1; WDR86 = WD repeat domain 86

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Biomarker Research

ISSN: 2050-7771

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