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Table 3 The association between empiric therapeutic AC and mortality of patients with COVID-19 based on the D-dimer level

From: Empiric use of anticoagulation in hospitalized patients with COVID-19: a propensity score-matched study of risks and benefits

D-Dimer level (ng/mL) N. of death/N. at risk (%) Univariate analysis
Total Therapeutic AC Prophylactic AC OR (95% CI) p value
≥500 150/230 (65.2) 57/92 (62.0) 93/138 (67.4) 0.788 (0.454–1.367) 0.397
≥1000 89/134 (66.4) 39/63 (61.9) 50/71 (70.4) 0.683 (0.332–1.402) 0.297
≥2000 65/103 (63.1) 29/49 (59.2) 36/54 (66.7) 0.725 (0.325–1.618) 0.432
≥3000 52/80 (65.0) 23/36 (63.9) 29/44 (65.9) 0.915 (0.364–2.302) 0.851
≥4000 37/59 (62.7) 16/29 (55.2) 21/30 (70.0) 0.527 (0.181–1.538) 0.239
≥5000 34/50 (68.0) 16/26 (61.5) 18/24 (75.0) 0.533 (0.158–1.799) 0.308
≥6000 30/44 (68.2) 13/21 (61.9) 17/23 (73.9) 0.574 (0.159–2.066) 0.393
≥7000 26/39 (66.7) 11/19 (57.9) 15/20 (75.0) 0.458 (0.117–1.789) 0.257
  1. OR Odds ratio, CI confidence interval, *Significant at p < 0.05