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Table 3 The association between empiric therapeutic AC and mortality of patients with COVID-19 based on the D-dimer level

From: Empiric use of anticoagulation in hospitalized patients with COVID-19: a propensity score-matched study of risks and benefits

D-Dimer level (ng/mL)

N. of death/N. at risk (%)

Univariate analysis

Total

Therapeutic AC

Prophylactic AC

OR (95% CI)

p value

≥500

150/230 (65.2)

57/92 (62.0)

93/138 (67.4)

0.788 (0.454–1.367)

0.397

≥1000

89/134 (66.4)

39/63 (61.9)

50/71 (70.4)

0.683 (0.332–1.402)

0.297

≥2000

65/103 (63.1)

29/49 (59.2)

36/54 (66.7)

0.725 (0.325–1.618)

0.432

≥3000

52/80 (65.0)

23/36 (63.9)

29/44 (65.9)

0.915 (0.364–2.302)

0.851

≥4000

37/59 (62.7)

16/29 (55.2)

21/30 (70.0)

0.527 (0.181–1.538)

0.239

≥5000

34/50 (68.0)

16/26 (61.5)

18/24 (75.0)

0.533 (0.158–1.799)

0.308

≥6000

30/44 (68.2)

13/21 (61.9)

17/23 (73.9)

0.574 (0.159–2.066)

0.393

≥7000

26/39 (66.7)

11/19 (57.9)

15/20 (75.0)

0.458 (0.117–1.789)

0.257

  1. OR Odds ratio, CI confidence interval, *Significant at p < 0.05