Table 2 Biomarker status of elevated miR-21 across 13 neoplasias

1

AIDS-related non-Hodgkin lymphoma

125

Serum

miR-122, miR-223

Predictive

[53]

2

B-cell lymphoma

157

Serum

--

Prognostic

[54]

2

B-cell lymphoma

103

Serum

miR-155, miR-210

Predictive

[55]

3

Breast cancer

122

Serum

--

Predictive/prognostic

[56]

3

Breast cancer

120

Serum

miR-92a

Predictive

[57]

4

Colorectal cancer

330

Serum

miR-92a

Prognostic

[58]

4

Colorectal cancer

60DC / 40VC

Plasma

miR-1, miR-133a, miR-31, miR-135b

Predictive

[59]

4

Colorectal cancer

24DC / 342VC

Serum

--

Predictive/prognostic

[60]

5

Esophageal cancer

42

Serum

--

Predictive

[61]

6

Gastric cancer

42

Plasma

--

Prognostic

[62]

6

Gastric cancer

20DC / 120VC

Plasma

miR-223, miR-218

Predictive

[63]

7

Glioma

112

Plasma

miR-15b

Predictive

[64]

7

Glioma

60

Plasma

miR-128, miR-342

Predictive/prognostic

[65]

8

Hepatocellular carcinoma

80DC / 453VC

Serum

--

Predictive/prognostic

[66]

8

Hepatocellular carcinoma

57

Serum EV

miR-144

Predictive

[67]

8

Hepatitis B/hepatocellular carcinoma

137DC / 407DC / 390VC

Plasma

miR-122, miR-192, miR-223, miR-27a, miR-26a, miR-801

Predictive

[68]

9

Hodgkin lymphoma

62

Plasma

miR-494, miR-1973

Predictive

[69]

10

Lung cancer

176

Serum

miR-155, miR-197, miR-182

Predictive/prognostic

[46]

11

Osteosarcoma

40DC / 48VC

Plasma

miR-221, miR-106a

Prognostic

[70]

11

Osteosarcoma

95

Serum

--

Prognostic

[71]

12

Pancreatic cancer

50DC / 176VC / 68DC / 137VC

Serum

miR-20a, miR-24, miR-25, miR-99a, miR-185, miR-191

Predictive/prognostic

[72]

12

Pancreatic cancer

74

Plasma

miR-483

Predictive

[73]

13

Prostate cancer

28

Serum

miR-106b, miR-144, miR-375

Predictive

[74]

13

Prostate cancer

71

Plasma

miR-141, miR-221

Predictive

[75]