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Fig. 6 | Biomarker Research

Fig. 6

From: Single-cell map of diverse immune phenotypes in the acute myeloid leukemia microenvironment

Fig. 6

Dysfunctional/exhausted CD8+-T/NK subsets revealed by scRNA-seq analysis. a UMAP plot of NK/NKT-like population, GNLY+GZMH+CD8+ T population, and GZMK+GZMA+CD8+ T population. These 2901 cells can be divided into 6 subsets. b Dot plot showed the transcript expression pattern of cell-type genes. c Histogram showed the fractions of different cell-type in NK/NKT-like population, GNLY+GZMH+CD8+ T population, and GZMK+GZMA+CD8+ T population for each AML patient and healthy donors’ BM cells, colored based on cell type. d Dot plot showed the transcript expression pattern of memory-like CD8+ T-related genes

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