Fig. 5
From: Identification of pAKT as a pharmacodynamic marker for MER kinase in human melanoma G361 cells
Comparison of IC50 for pAKT inhibition between H1299 and G361 cell lines. a Nonlinear regression analysis of inhibitor concentration and phosphorylated AKT (pAKT) response for 4 AXL/MER kinase inhibitors in H1299 and G361 cell lines. Results are shown as mean ± standard deviation (SD) of 3 wells. b Comparison of cellular half-maximal inhibitory concentration (IC50) for pAKT inhibition and enzymatic activities for AXL/MER