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Fig. 4 | Biomarker Research

Fig. 4

From: PSCA is a target of chimeric antigen receptor T cells in gastric cancer

Fig. 4

Anti-PSCA CAR-T cells efficiently reduced tumor progression in BGC-823 models. a. Schematic representation depicting the time course of the experiment. b. Tumor volume was calculated according to the following formula: length × width2/2. c. Tumor weight of BGC-823 subcutaneously injected mice. Error bars denote the s.e.m., and the results were compared with one-way ANOVA. *p < 0.05; **p < 0.01; ***p < 0.001. d. Percentage of T cells in the tumor of the BGC-823 models. e. Percentage of T cells in the PB of the BGC-823 models and representative FACS plots of the i.v group and the p.t group, respectively. f. Percentage of T cells in the spleen of the BGC-823 models and representative FACS plots of the i.v group and the p.t group, respectively. Error bars denote the s.e.m., and the results were compared with one-way ANOVA. *p < 0.05; **p < 0.01; ***p < 0.001

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