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Table 2 Post-transplant complications

From: Development of acoustically isolated extracellular plasma vesicles for biomarker discovery in allogeneic hematopoietic stem cell transplantation

 

# affected patients (pat-ID)

Complicationa

Pre/Tx

week 1

week 2

week 3

week 4

week 6

week 8

week 10/11

week12

Early infection, neutropenic (week 1–4)

4b (3, 10, 11, 19)

7 (1,2,5, 7,11,12,19)

11 (2,5,6,8,9,11,12,13,16,19,20)

5 (5,9,12,14,16)

2 (5,16)

    

Late Infection (≥ week 5)

       

2 (1,8)

1 (1)

GvHD (all grades)

  

1

1

2

7

7

7

5

Grade I

  

1 (2)

1 (2)

2 (1,8)

7 (1,2,4,7,8,9,17)

5 (1,2,6,7,17)

5 (2,4,5,6,7)

4 (2,4,10,18)

Grade II/III

      

2 (8,19)

2 (8,19)

1 (8)

CMV reactivation

     

3 (1,4,16)

2 (16,19)

1 (19)

1 (8)

  1. aDefinition of complications: Infection (use of broad spectrum i.v. antibiotics because of fever > 38.5 °C plus CRP > ULN [upper limit of normal]); GvHD (overall grades according to guidelines from Mount Sinai Acute GvHD International Consortium; CMV reactivation (detectable copies of CMV DNA in the peripheral blood plus CMV-active antiviral treatment)
  2. b neutropenic fever on day of transplantation due to antithymocyte globulin (ATG)