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Fig. 2 | Biomarker Research

Fig. 2

From: Development of acoustically isolated extracellular plasma vesicles for biomarker discovery in allogeneic hematopoietic stem cell transplantation

Fig. 2

Increased numbers of EVs are released into the plasma after allo-HSCT. a Transmission electron image of acoustically enriched EVs, bar = 100 nm. b Size distribution of EVs as measured by nanoparticle tracking analysis (NTA). Absolute numbers of EVs (c) and fold change of EVs (d) (per 50 μL diluted plasma) increased after allo-HSCT compared to pre-transplantation values. Pre-transplantation = week 0; weeks after transplantation = week 1, 2, 3, 4, 6, 8, 10, 11, 12. e After transplantation, EV sizes slightly increased over time compared to week 0. f Size distribution of EVs at different time points before and after transplantation. EV numbers are indicated per 50 μL diluted plasma. Data in b and c are presented as mean ± SEM of 10 patients

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Biomarker Research

ISSN: 2050-7771

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