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Fig. 5 | Biomarker Research

Fig. 5

From: Longitudinal CITE-Seq profiling of chronic lymphocytic leukemia during ibrutinib treatment: evolution of leukemic and immune cells at relapse

Fig. 5

Ibrutinib-induced changes in B leukemic cells. a Individual CD expression; b UMAP representation and quantification of genes signatures; c UMAP representation of BCL-2 expression; d Semi-quantification of BCL-2: M0 (), M27 (); e In vitro B cell depletion induced by ibrutinib (IBR) or venetoclax (VEN) before treatment (M0) and during progression (M27)

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Biomarker Research

ISSN: 2050-7771

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