Table 3 Performance of promoter gene methylation as biomarkers for detection of Esophageal Cancer according histological subtype
From: A DNA methylation-based test for esophageal cancer detection
Gene | Sensitivity % | Specificity % | Accuracy % | LH + | LH- | |
|---|---|---|---|---|---|---|
EAa | COL14A1 | 80.00 | 71.43 | 75.00 | 2.80 | 0.28 |
ZNF569 | 82.5 | 96.4 | 90.5 | 22.69 | 0.18 | |
Panel-EA | 97.50 | 71.43 | 82.29 | 3.41 | 0.04 | |
ESCCb | GPX3 | 52.1 | 91.132 | 73.1 | 5.83 | 0.53 |
ZNF569 | 58.3 | 96.4 | 78.6 | 16.04 | 0.43 | |
Panel-ESCC | 75.00 | 87.50 | 81.73 | 6.00 | 0.29 |