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Table 3 Correlations between cytokines and adipokines with clinical variables: including disease activity index, rSLEDAI score, individual markers of renal activity or renal dysfunction and glucocorticoids doses in SLE-patients

From: Assessment of serum macrophage migration inhibitory factor (MIF), adiponectin, and other adipokines as potential markers of proteinuria and renal dysfunction in lupus nephritis: a cross-sectional study

  MIF (ng/mL)
n = 196
Leptin (ng/mL)
n = 196
Adiponectin (μg/mL)
n = 196
Resistin (ng/mL)
n = 188
rs p rs p rs p rs p
Age, years −0.21 0.003 0.04 0.62 −0.13 0.07 0.03 0.67
BMI, kg/m2 − 0.06 0.36 0.47 < 0.001 −0.27 < 0.001 0.21 0.004
Disease duration, years −0.21 0.004 0.06 0.38 −0.07 0.35 0.06 0.42
SLEDAI, score 0.04 0.54 0.09 0.22 0.11 0.13 0.03 0.70
rSLEDAI, score −0.003 0.96 0.1 0.17 0.21 0.004 0.13 0.07
MEX-SLEDAI, score 0.02 0.75 0.1 0.13 0.16 0.03 0.04 0.58
SLICC/ACR, score 0.15 0.15 0.09 0.24 0.03 0.65 0.19 0.01
Proteinuria, g/24 h −0.02 0.77 0.18 0.01 0.19 0.009 0.26 < 0.001
Creatinine, mg 0.27 0.04 0.12 0.1 0.16 0.22 0.18 0.02
eGFR (mL/min/m2) 0.11 0.13 0.17 0.02 −0.15 0.05 0.01 0.91
Creatinine clearance (mL/min) 0.07 0.39 0.1 0.89 −0.01 0.18 −0.06 0.44
GCs dose, mg/day −0.04 0.63 0.1 0.15 0.17 0.02 0.16 0.03
  1. rs Spearman Rank Correlation, BMI Body mass index, GCs Glucocorticoids, SLE Systemic Lupus Erythematosus, SLEDAI SLE Disease Activity Index, rSLEDAI Renal SLEDAI, MEX-SLEDAI Mexican version of SLEDAI, SLICC/ACR Systemic Lupus International Collaborating Clinics/American College of Rheumatology, eGFR Estimated glomerular filtration rate. Glucocorticoids included: prednisone or deflazacort. GCs dose were expressed as equivalent to prednisone. Spearman Rank Correlation test p < 0.05