Fig. 3From: Advances in RNA cytosine-5 methylation: detection, regulatory mechanisms, biological functions and links to cancerNSUN2-modified m5C methylation in tRNALeu-CCA maintains tRNA stability in response to stress and ultimately promotes protein synthesis. Additionally, DNMT2-dependent methylation of tRNAAsp-GTC and tRNAGly-GCC protects them from cleavage, and this function is strengthened by NSUN2-modified m5C methylation of tRNAAsp-GTC and tRNAGly-GCCBack to article page