LncRNA SNHG16 as a potential biomarker and therapeutic target in human cancers

Biomarker Research

Table 2 In vitro functional characterization of SNHG16 in cancer

Cancer type	Effect on viability/proliferation	Effect on apoptosis	Effect on invasion/metastasis	Effect on chemoresistance	Ref.
Acute Lymphoblastic Leukemia	promote	–	promote	–	[22]
Bladder cancer	promote	inhibit	promote	–	[24,25,26]
Breast cancer	–	–	promote	–	[27]
Cervical cancer	promote	–	promote	–	[28, 29]
Colorectal cancer	promote	inhibit	promote	–	[30, 31]
Diffuse large B-cell lymphoma	promote	inhibit	–	–	[33]
Endometrial carcinoma	promote		–	–	[34]
Esophageal squamous cell carcinoma	promote	inhibit	promote	–	[35, 36]
Gastric Cancer	promote	inhibit	promote	–	[35, 37, 39, 40]
Glioma	promote	inhibit	promote	–	[41,42,43]
Hepatocellular carcinoma	inhibit	–	–	inhibit	[44]
Hepatocellular carcinoma	promote	inhibit	promote	promote	[45,46,47,48,49,50]
Neuroblastoma	promote	inhibit	promote	–	[20, 51, 52]
Non-small cell lung cancer	promote	inhibit	promote	–	[54]
Oral squamous cell carcinoma	promote	inhibit	promote	–	[55]
Osteosarcoma	promote	inhibit	promote	–	[56,57,58,59]
Ovarian cancer	promote	–	promote	–	[60]
Pancreatic cancer	promote	–	promote	–	[61]
Papillary thyroid cancer	promote	inhibit	promote	–	[62]
Retinoblastoma	promote	inhibit	–	–	[63]

ISSN: 2050-7771