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Table 2 Clinical characteristics of the training cohort related to cirrhosis

From: A radiomics-based model on non-contrast CT for predicting cirrhosis: make the most of image data

 

Spearman correlation analysis

Multivariable analysis

ROC analysis

Variables

r2 value

P value

b coefficient

P value

AUC

Cutoff value

Age (years)

0.021

.08

NA

NA

NA

NA

Sex (male, female)

0.003

.50

NA

NA

NA

NA

RBC (109/L)

0.020

.08

NA

NA

NA

NA

WBC (109/L)

0.078

.02

NA

.24

NA

NA

PLT (109/L)

0.106

< .001

NA

.07

NA

NA

Hb (g/L)

0.020

.08

NA

NA

NA

NA

ALT (U/L)

0.066

.002

0.060

.02

0.65 (0.56, 0.74)

25.9

AST (U/L)

0.073

.001

−0.092

.01

0.66 (0.57, 0.75)

32.6

ALP (U/L)

0.016

.12

NA

NA

NA

NA

GGT (U/L)

0.002

.57

NA

NA

NA

NA

LDH (U/L)

0.013

.16

NA

NA

NA

NA

TB (umol/L)

0.001

.65

NA

NA

NA

NA

CB (umol/L)

0.027

.04

NA

.56

NA

NA

ALB (g/L)

0.098

< .001

NA

.51

NA

NA

GLOB (g/L)

0.049

.006

0.219

.01

0.63 (0.54, 0.73)

33.9

TBA (umol/L)

0.066

.001

NA

.53

NA

NA

LAP (U/L)

0.000

.81

NA

NA

NA

NA

TC (mmol/L)

0.066

.002

NA

.50

NA

NA

HDL-C (mmol/L)

0.000

.86

NA

NA

NA

NA

LDL-C (mmol/L)

0.053

.005

NA

.44

NA

NA

Apo A1 (g/L)

0.009

.25

NA

NA

NA

NA

Apo B (g/L)

0.057

.003

NA

.24

NA

NA

CRP (mg/L)

0.006

.34

NA

.19

NA

NA

PT (s)

0.142

< .001

NA

.58

NA

NA

INR

0.149

< .001

16.558

< .001

0.73 (0.65, 0.82)

1.10

  1. Note. ——b coefficients are from multivariable logistic regression. Clinical variables found to be significantly related to cirrhosis through spearman correlation analysis entered into forward conditional logistic multivariate analysis. ALB albumin, ALP alkaline phosphatase, ALT alanine aminotransferase, Apo A1 apolipoprotein A1, Apo B apolipoprotein B, AST aspartate aminotransferase, AUC area under the curve, CB conjugated bilirubin, CRP C reactive protein, GGT glutamyl transpeptidase, GLOB globulin, Hb hemoglobin, HDL-C high density lipoprotein cholesterol, INR international normalized ratio, LAP leucine arylamidase, LDH lactate dehydrogenase, LDL-C low density lipoprotein cholesterol, PLT blood platelet, PT prothrombin time, RBC red blood cell, ROC receiver operating characteristic, TB serum total bilirubin, TBA total bile acid, TC total cholesterol, WBC white blood cell