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Table 2 Clinical characteristics of the training cohort related to cirrhosis

From: A radiomics-based model on non-contrast CT for predicting cirrhosis: make the most of image data

  Spearman correlation analysis Multivariable analysis ROC analysis
Variables r2 value P value b coefficient P value AUC Cutoff value
Age (years) 0.021 .08 NA NA NA NA
Sex (male, female) 0.003 .50 NA NA NA NA
RBC (109/L) 0.020 .08 NA NA NA NA
WBC (109/L) 0.078 .02 NA .24 NA NA
PLT (109/L) 0.106 < .001 NA .07 NA NA
Hb (g/L) 0.020 .08 NA NA NA NA
ALT (U/L) 0.066 .002 0.060 .02 0.65 (0.56, 0.74) 25.9
AST (U/L) 0.073 .001 −0.092 .01 0.66 (0.57, 0.75) 32.6
ALP (U/L) 0.016 .12 NA NA NA NA
GGT (U/L) 0.002 .57 NA NA NA NA
LDH (U/L) 0.013 .16 NA NA NA NA
TB (umol/L) 0.001 .65 NA NA NA NA
CB (umol/L) 0.027 .04 NA .56 NA NA
ALB (g/L) 0.098 < .001 NA .51 NA NA
GLOB (g/L) 0.049 .006 0.219 .01 0.63 (0.54, 0.73) 33.9
TBA (umol/L) 0.066 .001 NA .53 NA NA
LAP (U/L) 0.000 .81 NA NA NA NA
TC (mmol/L) 0.066 .002 NA .50 NA NA
HDL-C (mmol/L) 0.000 .86 NA NA NA NA
LDL-C (mmol/L) 0.053 .005 NA .44 NA NA
Apo A1 (g/L) 0.009 .25 NA NA NA NA
Apo B (g/L) 0.057 .003 NA .24 NA NA
CRP (mg/L) 0.006 .34 NA .19 NA NA
PT (s) 0.142 < .001 NA .58 NA NA
INR 0.149 < .001 16.558 < .001 0.73 (0.65, 0.82) 1.10
  1. Note. ——b coefficients are from multivariable logistic regression. Clinical variables found to be significantly related to cirrhosis through spearman correlation analysis entered into forward conditional logistic multivariate analysis. ALB albumin, ALP alkaline phosphatase, ALT alanine aminotransferase, Apo A1 apolipoprotein A1, Apo B apolipoprotein B, AST aspartate aminotransferase, AUC area under the curve, CB conjugated bilirubin, CRP C reactive protein, GGT glutamyl transpeptidase, GLOB globulin, Hb hemoglobin, HDL-C high density lipoprotein cholesterol, INR international normalized ratio, LAP leucine arylamidase, LDH lactate dehydrogenase, LDL-C low density lipoprotein cholesterol, PLT blood platelet, PT prothrombin time, RBC red blood cell, ROC receiver operating characteristic, TB serum total bilirubin, TBA total bile acid, TC total cholesterol, WBC white blood cell