Table 1 Characteristics of included studies
Cai | Qi | Case serie | China | Shenzhen | Single center | Hospital | Retrospective | Non-servere Vs Servere | 417 | 85 | NR | 233 | NR | NR | NR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cai | Q | Case serie | China | Shenzhen | Single center | Referal hospital | Retrospective | Non-servere Vs Servere | 298 | 58 | 62.5 | 240 | 41 | Liver diseases:13.9%; Type II diabetes:13.8%; Hypertension:37.9%; Cardiac diseases:22.4%; | Liver diseases:8.3%; Type II diabetes:4.2; Hypertension:10.4; Cardiac diseases:5.0% |
Chen | X | Case serie | China | Chongqing | Single center | Hospital | Retrospective | Non-servere Vs Servere | 78 | 15 | NR | 63 | NR | NR | NR |
Chen | G | Case serie | China | Wuhan | Single center | Hospital | Retrospective | Moderate Vs Severe | 21 | 11 | 61 | 10 | 52 | Hypertension: 36.4%; diabetes: 18.2% | Hypertension: 10%; diabetes:10% |
Fan | B | Case serie | Singapore | Unclear | Single center | Hospital | Prospective | ICU VS No-ICU | 67 | 9 | 54 | 58 | 41 | NR | NR |
Feng | Y | Case serie | China | Wuhan | Multicenter | Hospital | Retrospective | Moderate Vs Critical | 476 | 70 | 61 | 352 | 51 | Hypertension: 35.7%; diabetes 8.6%; cardiovascular diseases: 17.1%; malignancy: 8.6%;COPD: 15.7%;immunosuppression: 7.1%; | Hypertension: 20.7%;diabetes 9.1%; cardiovascular diseases 6%; malignancy: 1.4%;COPD: 2.3%;immunosuppression: 0.6%; |
Guan | W | Case serie | China | Unclear | Multicenter | Unclear | Retrospective | Admission to an intensive care unit (ICU), use of mechanical ventilation, or death | 1099 | 173 | 52 | 926 | 45 | Hepatitis B: 2.4%; Diabetes:16.2%;Hypertention: 23.7%;COPD:3.5%; CHD: 5.8%; Cerebro-Vas diseases: 2.3%;Immunodeficiency:0%;Cancer: 1.7% | Hepatitis B: 0.6%; Diabetes: 5.7%;Hypertention:13.4%;COPD: 0.6%; CHD: 1.8%; Cerebro-Vas diseases:1.2%;Immunodeficiency:0.2%;Cancer:0.8% |
Han | H | Cross sectional | China | Wuhan | Single center | Hospital | Prospective | Ordinary Vs Severe | 94 | 35 | NR | 49 | NR | NR | NR |
Huang | C | Case serie | China | Wuhan | Single center | Hospital | Prospective | Non-servere Vs Servere | 41 | 13 | 49 | 28 | 49 | Diabetes:8%;Hypertention: 15%;COPD:8%; CVD: 23%;Immunodeficiency:%;Cancer: 0% | Diabetes: 25%;Hypertention: 14%;COPD:0%;CVD: 11%;Cancer: 4% |
Li | Y | Case serie | China | Huazhong | Single center | Department of Thoracic Surgery | Retrospective | Non-servere Vs Servere | 25 | 9 | NR | 16 | NR | Hypertention: 11.1%;COPD:44.4%;diabetes:11.1%;CHD: 11.1 | Hypertention:6.3%;COPD:6.3%;diabetes: 0%;CHD:18.8 |
Li | K | Case serie | China | Unclear | Single center | Hospital | Retrospective | Non-servere Vs Servere | 83 | 25 | 53.7 | 58 | 41 | Hypertention:8%;COPD: 16.0%;diabetes:28.0%;CHD: 4.0% | Hypertention5.2%;COPD: 1.7%;diabetes:0.0%;CHD:0.0% |
Liu | Y | Case serie | China | Shenzhen | Single center | Hospital | Retrospective | Mechanical ventilation VS No Mechanical ventilation | 12 | 6 | 64.5 | 6 | 52 | Hypertention:17.6%;COPD:%;diabetes:16.7%;CHD:33.3%;cancer:0%;chronic liver diseases:0%; chronic renal diseases:16.7% | |
Liu | W | Case serie | China | Wuhan | Multicenter | Hospital | Retrospective | Common Vs Severe | 78 | 8 | NR | 70 | NR | Hypertention:10.3%;COPD: 5.1%;diabetes:6.4%;cancer:5.1% | |
Mao | L | Case serie | China | Wuhan | Multicenter | Neurology | Retrospective | Non-servere Vs Servere | 214 | 88 | 58.2 | 126 | 48.9 | Hypertention:36.4%; diabetes: 17.0%; cardiac/cerebral disease: 8.0%; Cancer: 5.7%; chronic kidney disease:2.3% | Hypertention: 15.1%; diabetes:11.9%; cardiac/cerebral disease:6.3%; Cancer:6.3%; chronic kidney disease:3.2% |
Qian | G | Case serie | China | Zhejiang | Multicenter | Hospital | Retrospective | Non-servere Vs Servere | 91 | 9 | 66 | 82 | 49 | NR | NR |
Qin | C | Case serie | China | Tongji | Single center | Hospital | Retrospective | Non-servere Vs Servere | 452 | 286 | 61 | 166 | 53 | Hypertention:36.7%;COPD: 3.1%;diabetes:18.5%;cancer:3.5%;CVD:8.4;CeVD:2.8%; chronic liver diseases: 1%;Tuberculosis:2.4%; chronic kidney diseases: 2.1% | Hypertention:18.1%;COPD: 1.8%;diabetes:13.3%;cancer:2.4%;CVD:1.8%;CeVD:1.8%; chronic liver diseases:1.8%;Tuberculosis:1.2%; chronic kidney diseases: 2.4% |
Qiu | H | Case serie | China | Zhejiang | Multicenter | Paediatric | Retrospective | Mild Vs Moderate | 36 | 19 | 9 | 17 | 7.5 | NR | NR |
Qu | R | Case serie | China | Huizhou | Single center | Hospital | Retrospective | Non-servere Vs Servere | 30 | 3 | 60 | 27 | 49.4 | NR | NR |
Ruan | Q | Case serie | China | Jin,Tongji | Multicenter | Hospital | Retrospective | Death Vs Discharge | 150 | 68 | NR | 82 | NR | NR | NR |
Wan | S | Case serie | China | Chongqing | Single center | Hospital | Retrospective | Non-servere Vs Servere | 135 | 40 | 56 | 95 | 44 | Hypertention:10%;COPD:10%;diabetes:22.5%;cancer: 7.5%;CVD:15%;chronic liver diseases:2.5%; pulmonary diseases:2.5% | Hypertention:9.4%;COPD:0%;diabetes: 3.1%;cancer:1.5%;CVD:1%; chronic liver diseases: 1%;Tuberculosis: %;diseases:0% |
Wang | Z | Case serie | China | Wuhan | Multicenter | Hospital | Retrospective | Non-servere Vs Servere | 69 | 14 | 70.5 | 55 | 37 | Hypertention:36%;COPD: 14%;diabetes:43%;cancer: 7%;CVD:36%;chronic liver diseases:0%; | Hypertention: 7%;COPD: 4%;diabetes: 2%;cancer: 5%;CVD:5%;chronic liver diseases:2% |
Wang | R | Case serie | China | Fuyang | Single center | Hospital | Retrospective | Non-servere Vs Servere | 125 | 25 | 49.4 | 100 | 39.7 | Comorbidities: 48% | Comorbidities:22% |
Wang | D | Case serie | China | Wuhan | Single center | Hospital | Retrospective | Non-servere Vs Servere | 138 | 36 | 66 | 102 | 51 | Hypertention:58.3%;COPD: 8.3%;diabetes:22.2%;cancer:11.1%;CVD:25.0%;chronic liver diseases:0%; CeVD:16.7%;HIV:0% | Hypertention:21.6%;COPD:1.0%;diabetes:5.9%;cancer: 5.9%;CVD:10.8%;chronic liver diseases:3.9%; CeVD:1.0%;HIV:2.0% |
Wu | C | Case serie | China | Wuhan | Single center | Hospital | Retrospective | Survivor Vs Non-survivor | 201 | 44 | 68.5 | 40 | 50 | aHypertention:36.4%; diabetes:25.0%; CVD:9.1% | aHypertention:17.5%; diabetes:12.5%;CVD:2.5% |
Xu | Y | Case serie | China | Unclear | Single center | Radiology | Retrospective | Mild/Moderate/Severe/critical | 50 | 3 | NR | 9 | NR | NR | NR |
Yang | X | Case serie | China | Wuhan | Single center | Hospital | Retrospective | Survivor Vs Non-survivor | 52 | 32 | 64.6 | 20 | 59.7 | aCOPD:6%;diabetes:22%;cancer:3%;CVD:9%;chronic liver diseases:0%; CeVD:22% | aCOPD:10%;diabetes:10%;cancer:5%;CVD:10%;chronic liver diseases:0%;CeVD:0% |
Young | B | Case serie | Singapore | NR | Multicenter | Hospital | Retrospective | Require Vs not require supp Oxygen | 18 | 6 | 56 | 12 | 37 | Comorbidities:67% | Comorbidities:8% |
Yun | L | Case serie | China | Shanghai | Single center | Hospital | Retrospective | No-servere Vs Servere | 292 | 21 | 65.5 | 271 | 48.7 | NR | NR |
Zhang | J | Case serie | China | Wuhan | Multicenter | Hospital | Retrospective | Non-servere Vs Servere | 140 | 58 | 64 | 82 | 51.5 | Hypertention:37.9%; COPD:3.4%; diabetes:13.8%;CHD:6.9%;liver diseases:6.9%; CeVD: 3.4% | Hypertention:24.4%; COPD:0%; diabetes:11.0%;CHD:3.7%;liver diseases:5.0%; CeVD: 1.2% |
Zheng | F | Case serie | China | Changsha | Single center | Hospital | Retrospective | Non-servere Vs Servere | 161 | 30 | 57 | 131 | 40 | Hypertention:40%; COPD:6.7%; diabetes:6.7%; CHD:6.7%;chronic liver diseases:3.1%; CeVD:3.3% | Hypertention:7.6%; COPD:3.1%; diabetes:3.8%;CHD:1.5%;chronic liver diseases:0%;CeVD:2.3% |
Zhou | F | Case serie | China | Wuhan | Multicenter | Pulmonary hospital | Retrospective | Survivor Vs Non-survivor | 191 | 54 | 69 | 137 | 52 | a Hypertention:48%; COPD:7%; diabetes: 31%; cancer:0%; CHD:14%;chronic kidney diseases:4% | a Hypertention: 23%; COPD:1%; diabetes: 14%; cancer:1%; CHD:1%;chronic kidney diseases:1% |