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Table 3 The 3 samples in each group, KO (top half) and SP-A1 (bottom half), were compared to identify CMPs present in all 3 samples (triplets) or in 2-of-3 samples

From: Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1

  1. A total of 13 markers (0–12) were studied. The number of identical CMPs present within the 50 most abundant CMPs out of the 2228 total CMPs are listed in Fig. 3. Next a filter was used to select, from the total number of CMPs (i.e. 2228 for the sample shown), the 50 most abundant CMPs containing a particular marker. This was done for each of the 13 markers. Then, from the 50 most abundant CMPs for each marker, CMPs that were present in all three samples of each of the two groups (KO and SP-A1) were noted as “triplets.” Those present in 2 out of 3 samples were noted as “2-of-3” (x-2-3; 1-x-3, 1–2-x). For example, the designation x-2-3 denotes the absence of a CMP in sample 1 and its presence in samples 2 and 3). These numbers for the triplets and 2-of-3 are shown in columns labeled 0–12 for each marker. The total number of triplets, 2-of-3, and of triplets plus 2-of-3 samples are also given for the KO group and the SP-A1 group. These values were compared and found to be significantly different (*) using an aligned rank test (p = 0.0007). At the bottom of the table, the number of triplets that KO and SP-A1 cells have in common are listed, and below this there is a line giving the difference (KO – SP-A1) between the two groups (highlighted in yellow)