Fig. 5

Analysis of individual cells. An example of this analysis using cell #10 from the 5–27 sample (see also Fig. 4). Each selected cell was circumscribed with a utility called a “lasso tool.” The inner ring (arrow) shows the area being analyzed. The outer ring is shown as a necklace or string of beads and depicts the CMPs present in order of abundance within the circumscribed area. The abundance of each CMP in the circumscribed cell is proportional to the size of the beads. The CMP numbers for some of the beads are not shown in the screen shot in Panel (A), but can be seen in Panel (B), which shows the top 20 CMPs for the circumscribed cell (arrow). The colors and CMP numbers are automatically assigned by the TIS software and correspond to the list of CMPs (based on frequency) for the entire image with all cells in that sample (see Figs. 3 and 4)