Fig. 2
From: LOX family and ZFPM2 as novel diagnostic biomarkers for malignant pleural mesothelioma
Diagnostic potential of LOX family and ZFPM2. Using the GEO database (GSE2549), mRNA expression of known biomarker (a) or candidate genes (b) were analyzed in normal (n = 9) and MPM tissues (n = 40). Each dot represents one sample, values are mean ± SEM of each groups. Statistical analysis between normal and MPM groups was executed using unpaired Student t-test. (**** p < 0.0001, *** p < 0.001, ** p < 0.01, * p < 0.05). The In-let represents ROC curves illustrating diagnostic ability of known biomarkers (a) and candidates (b). X and Y axes stands for sensitivity as well as 1-specificity, respectively. Maximal sensitivity and specificity were determined by Youden’s method. AUC (Area Under Curve)