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Table 4 Percentage of positivity of tumor cells with 50 and 1% threshold

From: Immune biomarkers in thymic epithelial tumors: expression patterns, prognostic value and comparison of diagnostic tests for PD-L1

Positive tumor cells 50% threshold

TB3

TC

P value

TB3 and TC

PD-L1 E1L3N (LDT)

44 (83%)

10 (20%)

< 0,0001

54/103 (52%)

PD-L1 22C3 (CA)

41 (77%)

12 (24%)

< 0,0001

53/103 (51%)

PD-L1 SP142 on Dako (LDT)

42 (81%)

10 (20%)

< 0,0001

52/102 (51%)

PD-L1 SP142 on ventana (CA)

4 (29%)

1 (09%)

=0,3406

5/25 (20%)

PD-L1 Sp263 (CA)

45 (92%)

10 (23%)

< 0,0001

55/93 (53%)

Positive tumor cells 1% threshold

TB3

TC

P value

TB3 and TC

PD-L1 E1L3N (LDT)

51 (96%)

36 (72%)

=0,0007

87/103 (84%)

PD-L1 22C3 (CA)

49 (92%)

35 (70%)

=0,0033

84/103 (82%)

PD-L1 SP142 on Dako (LDT)

48 (92%)

33 (66%)

=0,0010

81/102 (79%)

PD-L1 SP142 on ventana (CA)

10 (71%)

6 (54%)

=0,4341

16/25 (64%)

PD-L1 Sp263 (CA)

48 (98%)

32 (73%)

=0,0005

80/93 (86%)