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Fig. 1 | Biomarker Research

Fig. 1

From: Epigenetic heterogeneity in cancer

Fig. 1

Disruption of the “epigenetic machinery” in cancer. Aberrant changes of major players of “epigenetic machinery” during cancer initiation, progression and metastasis. HATs, DOT1L, DNMT, EZH2, SUV39H1/2: representative writers (enzymes that establish DNA methylation or histone modifications); HDACs, JmjC–KDMs, LSDs, DNA demethylase: representative erasers (proteins that remove DNA methylation or histone modification marks)

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Biomarker Research

ISSN: 2050-7771

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