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Table 2 Association between prognostic value of PRDXs mRNA expression and different subclasses in BrCa

From: Comprehensive analysis of peroxiredoxins expression profiles and prognostic values in breast cancer

Subclasses Cases HR 95% CI P value Cases HR 95% CI P value
OS RFS
PRDX1
 Basal-like 241 0.66 0.40–1.09 0.104 618 1.02 0.80–1.32 0.850
 Luminal A 611 1.52 1.06–2.17 0.022 1933 1.23 1.06–1.49 0.009
 Luminal B 433 0.98 0.68–1.43 0.956 1149 1.20 0.99–1.46 0.060
 HER2 positive 117 1.27 0.66–2.42 0.470 251 1.31 0.89–1.92 0.170
PRDX2
 Basal-like 241 1.14 0.70–1.85 0.613 618 1.25 0.97–1.61 0.078
 Luminal A 611 1.42 0.99–2.02 0.056 1933 1.23 1.04–1.46 0.016
 Luminal B 433 0.99 0.67–1.44 0.960 1149 1.67 1.37–2.03 < 0.001
 HER2 positive 117 0.93 0.49–1.77 0.821 251 1.24 0.85–1.83 0.264
PRDX3
 Basal-like 241 0.77 0.47–1.26 0.299 618 0.77 0.60–1.00 0.046
 Luminal A 611 0.74 0.52–1.05 0.090 1933 0.87 0.73–1.03 0.112
 Luminal B 433 1.02 0.70–1.48 0.919 1149 1.17 0.96–1.41 0.115
 HER2 positive 117 0.59 0.30–1.15 0.118 251 0.73 0.49–1.07 0.102
PRDX4
 Basal-like 241 0.67 0.41–1.11 0.119 618 1.04 0.81–1.33 0.784
 Luminal A 611 1.58 1.10–2.27 0.012 1933 1.56 1.31–1.85 < 0.001
 Luminal B 433 1.55 1.06–2.27 0.023 1149 1.56 1.28–1.89 < 0.001
 HER2 positive 117 0.41 0.20–0.83 0.010 251 0.83 0.57–1.23 0.358
PRDX5
 Basal-like 153 1.09 0.58–2.06 0.790 360 1.71 1.23–2.37 0.001
 Luminal A 271 1.09 0.66–1.81 0.725 841 1.19 0.93–1.53 0.164
 Luminal B 129 0.58 0.29–1.15 0.117 407 0.95 0.70–1.29 0.752
 HER2 positive 73 1.59 0.71–3.54 0.253 156 1.34 0.85–2.11 0.213
PRDX6
 Basal-like 241 1.08 0.66–1.76 0.761 618 1.01 0.78–1.29 0.963
 Luminal A 611 1.49 1.04–2.13 0.027 1933 1.29 1.08–1.53 0.004
 Luminal B 433 0.95 0.65–1.37 0.771 1149 1.27 1.05–1.54 0.015
 HER2 positive 117 0.87 0.46–1.66 0.675 251 0.93 0.63–1.36 0.708