Table 2 Clinical trials of MSCs exosomes–based therapies
From: Exosomes from mesenchymal stem/stromal cells: a new therapeutic paradigm
Study title | Disease | Intervention | Phase | NCT |
|---|---|---|---|---|
Allogenic Mesenchymal Stem Cell-Derived Exosome in Patients With Acute Ischemic Stroke | Cerebrovascular Disorders | Biological: exosome | Phase 1 Phase 2 | NCT03384433 |
MSC-Exos Promote Healing of MHs | Macular Holes | Biological: exosomes derived from mesenchymal stem cells (MSC-Exo) | Early Phase 1 | NCT03437759 |
microRNAs Role in Pre-eclampsia Diagnosis | Preeclampsia | Biological: exosome | Complete | NCT03562715 |
Effect of Microvesicles and Exosomes Therapy on β-cell Mass in Type I Diabetes Mellitus (T1DM) | Diabetes Mellitus Type 1 | Biological: MSC exosomes. | Phase 2 Phase 3 | NCT02138331 |
Trial of a Vaccination With Tumor Antigen-loaded Dendritic Cell-derived Exosomes | Non Small Cell Lung Cancer | Biological: Dex2 | Phase 2 | NCT01159288 |
Serum Exosomal Long Noncoding RNAs as Biomarkers for Lung Cancer Diagnosis | Lung Cancer (Diagnosis) | Diagnostic Test: collect samples | Â | NCT03830619 |