Table 1 Characteristics and outcomes with and without early neurological deterioration

Female, n (%)

70 (51%)

9 (60%)

0.59

Age (years)

76.0 (65.0–82.0)

79.0 (68.5–86.0)

0.42

Systolic blood pressure (mmHg)

158 (138–191)

174 (138–183)

0.82

Diastolic blood pressure (mmHg)

87 (75–96)

81 (74–92)

0.32

Heart rate (per minute)

83 (72–92)

76 (60–91)

0.27

Respirations (per minute)

17 (16–18)

16 (15–18)

0.89

Temperature (°C)

36.4 (36.1–36.7)

36.5 (36.4–36.8)

0.43

Oxygen saturations (%)

96 (95–98)

97 (96–99)

0.06

 LAC ischaemia/haemorrhage (subtotal %)

31/6 (27%)

2/2 (27%)

0.98

 PAC ischaemia/haemorrhage (subtotal %)

39/5 (32%)

4/0 (27%)

0.67

 TAC ischaemia/haemorrhage (subtotal %)

31/6 (27%)

3/4 (46%)

0.11

 POC ischaemia/haemorrhage (subtotal %)

8/2 (7%)

0/0 (0%)

0.28

 Transient ischaemic attack^a

9 (7%)

–

–

Intravenous thrombolysis treatment (%)

56 (41%)

5 (33%)

0.59

Baseline NIHSS

7 (4–14)

13 (6–17)

0.26

24-36 h NIHSS

4 (1–10.25)

18 (13–25)

< 0.01

Minutes from onset to assay

133 (96–180)

104 (73–146)

0.15

Whole blood purine concentration (μM)

4.83 (3.00–9.02)

7.21 (4.77–10.65)

0.10

Mean [SD] whole blood purine concentration (μM)

7.65 [7.67]

11.3 [11.60]

0.26