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Table 1 Characteristics and outcomes with and without early neurological deterioration

From: The association between early neurological deterioration and whole blood purine concentration during acute stroke

  non-END (n = 137) END (n = 15) p-value
Female, n (%) 70 (51%) 9 (60%) 0.59
Age (years) 76.0 (65.0–82.0) 79.0 (68.5–86.0) 0.42
Systolic blood pressure (mmHg) 158 (138–191) 174 (138–183) 0.82
Diastolic blood pressure (mmHg) 87 (75–96) 81 (74–92) 0.32
Heart rate (per minute) 83 (72–92) 76 (60–91) 0.27
Respirations (per minute) 17 (16–18) 16 (15–18) 0.89
Temperature (°C) 36.4 (36.1–36.7) 36.5 (36.4–36.8) 0.43
Oxygen saturations (%) 96 (95–98) 97 (96–99) 0.06
Clinical subgroup
 LAC ischaemia/haemorrhage (subtotal %) 31/6 (27%) 2/2 (27%) 0.98
 PAC ischaemia/haemorrhage (subtotal %) 39/5 (32%) 4/0 (27%) 0.67
 TAC ischaemia/haemorrhage (subtotal %) 31/6 (27%) 3/4 (46%) 0.11
 POC ischaemia/haemorrhage (subtotal %) 8/2 (7%) 0/0 (0%) 0.28
 Transient ischaemic attacka 9 (7%)
Intravenous thrombolysis treatment (%) 56 (41%) 5 (33%) 0.59
Baseline NIHSS 7 (4–14) 13 (6–17) 0.26
24-36 h NIHSS 4 (1–10.25) 18 (13–25) < 0.01
Minutes from onset to assay 133 (96–180) 104 (73–146) 0.15
Whole blood purine concentration (μM) 4.83 (3.00–9.02) 7.21 (4.77–10.65) 0.10
Mean [SD] whole blood purine concentration (μM) 7.65 [7.67] 11.3 [11.60] 0.26
  1. aTransient ischaemic attack cannot co-exist with END. Variables are median (IQR) unless otherwise stated; END early neurological deterioration, NIHSS National Institutes of Health Stroke Scale, LAC lacunar circulation, PAC partial anterior circulation, TAC total anterior circulation, POC posterior circulation