TY - JOUR AU - Martin, Alexander J. AU - Dale, Nicholas AU - Imray, Christopher H. E. AU - Roffe, Christine AU - Smith, Craig J. AU - Tian, Faming AU - Price, Christopher I. PY - 2019 DA - 2019/04/03 TI - The association between early neurological deterioration and whole blood purine concentration during acute stroke JO - Biomarker Research SP - 7 VL - 7 IS - 1 AB - Early neurological deterioration (END) is common after stroke. Prediction could identify patients requiring additional monitoring and intervention. Purines, breakdown products of adenosine triphosphate which accumulate during acute hypoxia, may reflect the subclinical presence of vulnerable tissue. We considered whether whole blood purine concentration (WBPC) measurements during acute stroke were associated with subsequent END. SN - 2050-7771 UR - https://doi.org/10.1186/s40364-019-0158-y DO - 10.1186/s40364-019-0158-y ID - Martin2019 ER -