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Fig. 2 | Biomarker Research

Fig. 2

From: Elevated doublecortin-like kinase 1 serum levels revert to baseline after therapy in early stage esophageal adenocarcinoma

Fig. 2

a. ROC analysis illustrates that DCLK1 serum levels are a sensitive and specific measure of the presence of esophageal adenocarcinoma (n = 14) when compared to controls (n = 5) as indicated by an area under the curve (AUC) of 0.9714 (p = 0.0016). b. Similar results were calculated for Barrett’s esophagus (n = 9) compared to controls (AUC: 0.9111, p = 0.0136). c. Comparison of EAC serum after treatment (n = 6) demonstrated a more moderate but significant AUC of 0.8333 (p = 0.0209). d. Serum levels of DCLK1 are not significantly related to patient age (p = 0.66, Pearson r = 0.08)

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