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Fig. 1 | Biomarker Research

Fig. 1

From: Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis

Fig. 1

Histopathological examination in hematoxylin-eosin. a: BM at the initial diagnosis of PMF, showing hypercellularity with some fat cells left (circle), clusters of mature granulocytes (closed arrow), singular and groups of atypical megakaryocytes (open arrow). b: BM at follow up, showing maximal cellularity without any fat cells left, no organized hematopoiesis with only singular mature granulocytes, a few atypical megakaryocytes, and clusters of immature cells and blast cells (asterisk). (Pictures: Friedemann Leh, Department of Pathology, Haukeland University Hospital)

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