Fig. 8
a Immunohistochemistry showing caspase-6 staining in ovarian epithelium transition to ovarian tumor. (a) Caspase-6 staining with 10× magnification; (b) Caspase-6 staining with 40× magnification. Activated caspase-6 is absent or weakly expressed in normal looking ovarian surface epithelial cells with normal nuclei (green arrow) while it is overexpressed in the cytoplasm of tumor cells with large nuclei (red arrow). Thus, active caspase-6 expression is absent in normal tissue (green arrows) and over expressed in the adjacent tumorous section