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Table 3 Most predictive biomarkers and cluster members for serum water T2

From: Aptamer-based search for correlates of plasma and serum water T2: implications for early metabolic dysregulation and metabolic syndrome

Protein Name (Uniprot ID)a % Inc. MSEa Cluster Members
Endothelial cell-specific molecule 1 (Q9NQ30) 11.0 Bone sialoprotein 2, Bone morphogenetic protein 10
Glucokinase regulatory protein (Q14397) 8.0 2′-5′-oligoadenylate synthase 1, T-lymphocyte activation antigen CD86
Lactadherin (Q08431) 7.4 Hepatocyte growth factor receptor, Alpha-2-macroglobulin, Adrenomedullin, N terminal pro BNP
Vascular cell adhesion protein 1 (P19320) 6.1 Secreted frizzled-related protein 3, L-selectin
Receptor-type tyrosine-protein kinase FLT3 (P36888) 5.6 Serum amyloid P-component, Discoidin domain-containing receptor 2, Serine/threonine-protein kinase PAK 6, Heterogeneous nuclear ribonucleoprotein A/B
Semaphorin-6A (Q9H2E6) 5.2 Osteopontin, Leucine-rich repeat transmembrane protein FLRT3, Ephrin-B2, Ephrin-A5, NT-3 growth factor receptor, Kallikrein-8, Interleukin-1 receptor type 1, Iduronate 2-sulfatase, CD109 antigen, Cell adhesion molecule 1, Brother of CDO, SLIT and NTRK-like protein 5, Endoglin, Neuropilin-1
  1. aThe most predictive biomarkers are defined as those with ≥5% increase in mean squared error (MSE)