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Table 3 Most predictive biomarkers and cluster members for serum water T2

From: Aptamer-based search for correlates of plasma and serum water T2: implications for early metabolic dysregulation and metabolic syndrome

Protein Name (Uniprot ID)a

% Inc. MSEa

Cluster Members

Endothelial cell-specific molecule 1 (Q9NQ30)

11.0

Bone sialoprotein 2, Bone morphogenetic protein 10

Glucokinase regulatory protein (Q14397)

8.0

2′-5′-oligoadenylate synthase 1, T-lymphocyte activation antigen CD86

Lactadherin (Q08431)

7.4

Hepatocyte growth factor receptor, Alpha-2-macroglobulin, Adrenomedullin, N terminal pro BNP

Vascular cell adhesion protein 1 (P19320)

6.1

Secreted frizzled-related protein 3, L-selectin

Receptor-type tyrosine-protein kinase FLT3 (P36888)

5.6

Serum amyloid P-component, Discoidin domain-containing receptor 2, Serine/threonine-protein kinase PAK 6, Heterogeneous nuclear ribonucleoprotein A/B

Semaphorin-6A (Q9H2E6)

5.2

Osteopontin, Leucine-rich repeat transmembrane protein FLRT3, Ephrin-B2, Ephrin-A5, NT-3 growth factor receptor, Kallikrein-8, Interleukin-1 receptor type 1, Iduronate 2-sulfatase, CD109 antigen, Cell adhesion molecule 1, Brother of CDO, SLIT and NTRK-like protein 5, Endoglin, Neuropilin-1

  1. aThe most predictive biomarkers are defined as those with ≥5% increase in mean squared error (MSE)