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Fig. 1 | Biomarker Research

Fig. 1

From: Phosphatidylinositol 3-kinase-δ (PI3K-δ) is a potential therapeutic target in adult T-cell leukemia-lymphoma

Fig. 1

PI3K activity and expression of PI3K-δ in ATL cells. a The activity of PI3K was quantified by PI3-Kinase Activity ELISA kit (Echelon). Whole-cell lysates were extracted from isolated CD4+ cells using Dynabeads (Invitrogen) from the PBMCs of healthy donors (n = 4) and ATL patients (n = 8). b PI3K-δ expression was identified by immunoblotting using the PBMCs of HTLV-1 uninfected healthy donors (n = 4), and ATL patients in whom the ATL clone constituted more than 75% of PBMCs (n = 11)

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