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Fig. 3 | Biomarker Research

Fig. 3

From: Kinomic profiling of glioblastoma cells reveals PLCG1 as a target in restricted glucose

Fig. 3

Proteins and phosphorylation sites corresponding to peptides differentially phosphorylated in restricted glucose. All peptides with a Log2 change > 0.3 (a) or < − 0.3 (b) when GBM456 (blue) or GBM14 (red) cells were cultured in low glucose in comparison to standard conditions are indicated. The Venn Diagram shows overlapping peptides in the center that have Log2 changes indicated above in both cell types. Peptides for which there was at least a > 0.5 Log2 change in one cell type and > 0.2 Log2 change in the other are also shown in the overlapping region in a. Peptides for which there was at least a < − 0.5 in one cell type and < − 0.2 Log2 change in the other are also shown in the overlapping region in b. The predominant common changes occur at tyrosine phosphorylation sites

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